Protein Pacing: Why Distribution Still Matters While total daily protein intake matters most, how you distribute that protein can matter, especially during weight loss
Lilleskov, Maurine
A dual GLP-1-estrogen conjugate (GE) designed to selectively deliver estrogen to GLP-1R + cells induced substantial weight loss in mice without evidence of systemic estrogenic effects, as assessed by uterine weight and growth of estrogen-dependent breast cancer xenografts (Kanoski et al., 2011)
It has also been demonstrated in a randomized, placebo-controlled, double-blind study that LG improved glucose metabolism and cognition in AD patients (76)
You still get appetite regulation, improved insulin sensitivity, and steady fat loss, but with significantly fewer side effects and a much lower risk of the muscle wasting that concerns people at higher doses
Many cases improve with routine habits