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We show here that the Michael acceptor methylene quinuclidinone (MQ), the active form of APR-246, is a potent direct inhibitor of Trx1 and Grx1 by reacting with sulfhydryl groups in the enzymes

Results of phase III study of Enspryng in patients with generalized myasthenia gravis [press release]

Therefore, further investigation into the development of TMAO and kidney diseases is required (Figure 10B)