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Ozempic FDA-approved for type 2 diabetes (2017)
Naturally occurring copper tripeptide that activates fibroblasts to upregulate collagen I/III/IV and elastin synthesis, inhibits MMP-1/2/9 collagen degradation enzymes, activates lysyl oxidase for collagen cross-linking, stimulates wound bed angiogenesis via VEGF/FGF-2, and activates Nrf2 antioxidant response element genes
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Research suggests that B7-33 influences cellular pathways that regulate fibrosis, making it an interesting subject for scientists exploring post-injury recovery
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