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A large preclinical toxicity program run across mice, rats, rabbits, and dogs found BPC-157 well tolerated with no serious treatment-related toxicity, no identifiable lethal dose, and no genotoxic or teratogenic signal, which is the strongest safety data point available by Xu 2020

If additional glycemic control is needed , increase the dosage to 2 mg once weekly after at least 4 weeks on the 1 mg dosage

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