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When Cochrane reviewers grade an evidence base as very low quality despite a positive pooled effect, this is usually what they are reacting to: not that the benefit is fake, but that the conditions under which it was measured are the conditions that reliably make benefits look bigger than they are

Individual CES-D scores were also categorized into 3 groups based on total score, including minimal/mild (total scores 015), moderate (total scores 1624) and severe (total scores 25) (84, 85)

[PMID: 9443950] PubMed record related to this compound for laboratory literature review

Many peptides demonstrate similar potency patterns

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