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USA 92 , 983987 (1995)
Generally, a dose by intravenous 600-1200mg weekly once is recommended for skin lightening
References Markle HV, Greenway DC
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No adverse effects, allergic reactions, or irritation have been reported at concentrations up to 3%
The increased oxidative stress seems to be the second hit in the progression from NAFL to NASH: the increase in ROS and consequently in lipid peroxidation has been associated to hepatocellular damage, inflammation, and eventual fibrosis due to the activation of hepatic stellate cells
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