in contrast, the 130 amino acids residues of GhGPX9, 10 may be a mitochondrial or chloroplastic targeting peptide, as predicted by iPSORT and TargetP, which were used to predict the subcellular localisation of eukaryotic proteins ( Differential expression pattern and subcellular localisation of GhGPX products To determine which tissues normally express GhGPX genes, gene-specific primers were used for transcription analysis in roots, stems, flowers, cotyledons and leaves of G
Cell and Tissue Research , 347 (1), 103116
Research Applications Antioxidant & Cellular-Defense Research Glutathione is widely researched for its interaction with intracellular antioxidant systems and oxidative-stress regulation pathways
Fly strains UAS-GFP (Bloomington Stock #6874), TH-Gal4 (Bloomington Stock #8848), CatalaseRNAi (Bloomington Stock #34020) and PHGPx (Bloomington Stock #33939), were obtained from Bloomington stock center, Indiana, along with park 13 (Bloomington Stock #79210) as the Parkinsonian disease model
Isoloquiritigenin led to apoptosis and autophagy-mediated cell death by decreasing cyclin D1 expression as increasing the number of cells in the sub-G1 phase, which inhibited the proliferation of breast cancer cells (141)
Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD