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& Ballester, B
The standard regimen involves: Loading doses without neurological involvement : 1 mg intramuscularly three times a week for 2 weeks [3] [8] Loading doses with neurological involvement : 1 mg intramuscularly on alternate days until no further improvement [3] [8] Maintenance therapy : 1 mg every 23 months for life in cases of pernicious anaemia or irreversible malabsorption (every 2 months if neurological involvement) [3] [8] This aggressive approach aims to prevent irreversible neurological damage, though recovery of established neuropathy may be incomplete, particularly if treatment is delayed
Prior B12 values show whether the elevation is persistent or already on its way down, and any CBC, liver tests, or renal function already on file may point to a cause before anything new is ordered
Association between metformin and vitamin B12 deficiency in patients with type 2 diabetes
Cognitive symptoms like memory loss and brain fog also occur
The compounds mechanism of action makes it relevant to research on metabolic disorders, obesity, and energy metabolism
