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Systemic versus topical approach Unlike KPV and GHK-Cu, which are primarily studied as topical applications for skin conditions, TB-500 works systemically

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note an increase in the average myocardial performance index which was directly correlated to the frequency of relapses, disease duration, and a history of hypertension and hypercholesterolemia (115)

[26] None of the studies reported significant adverse effects or follow-up beyond the study period (Table 1)