In musculoskeletal research models, it has been associated with altered fibroblast behavior and extracellular matrix organization
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Stopping GLP-1 medications typically leads to weight regain, with most people regaining 50-70% of lost weight within 12 months as appetite and metabolic adaptations return
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Their pharmacological targets, clinical indications, and regulatory statuses are markedly different, and they should not be considered interchangeable or directly comparable therapeutic alternatives