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Key Points Semaglutide reduces appetite within the first two weeks, with most people reaching steady levels by 4-5 weeks of treatment Weight loss averages 2% by four weeks and 4% by eight weeks, with clinical studies showing a 15% average loss over 68 weeks Blood sugar improvements occur gradually, with A1C reductions of 1.2%-2.2% seen between 26-40 weeks, depending on medication type The medication works best when paired with healthy eating habits and regular physical activity for optimal results If youre taking semaglutide for weight loss or diabetes, youre probably wondering when youll start seeing results

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World J Methodol 2014;4:133-43

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Ozempic is FDA-approved for chronic weight management, while Wegovy is FDA-approved for type 2 diabetes and may be prescribed off-label for weight loss at a providers discretion