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That's $400 a month," stated Favella

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"Dual GIP and GLP-1 Receptor Agonist Tirzepatide Improves Beta-cell Function and Insulin Sensitivity in Type 2 Diabetes." Journal of Clinical Investigation

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The Clinical Reality Check: STEP 1, STEP 4, SELECT, and the 52% Dropout Trial data and real-world data tell two different stories

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Patients with polycystic ovary syndrome (PCOS) who have both insulin resistance and obesity might benefit from this combination, as metformin is commonly used off-label in PCOS management (NICE CKS) and Wegovy can address weight-related aspects of the condition

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For example, tirzepatide may reduce the effectiveness of oral contraceptives, and patients taking warfarin with any GLP-1 receptor agonist should consider more frequent INR monitoring when starting or stopping therapy

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