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Simulation Results of in Silico Modeling of Oxidative Stress with Only Formaldehyde Detoxification Pathways of C1 Metabolism Herein, the temporal dynamics of formaldehyde and glutathione (GSH), from in silico modeling of oxidative stress and integration of the formaldehyde detoxification pathway, one of the three critical elements of the C1 metabolism, is presented in Figure 8(a) and Figure 8(b), respectively

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225 In MASLD animal models, quercetin reduces hepatic triglyceride levels, increases AMPK phosphorylation, and improves insulin sensitivity, as reflected by HOMA-IR index reductions