The GLP-1 pathway governs appetite, satiety, gastric emptying, and glucose regulation
Increased feelings of fullness : Slows down digestion, making you feel fuller for longer periods Improved health outcomes : Reduces the risk of weight-related health conditions such as type 2 diabetes, hypertension, and cardiovascular disease
The elderly (reduced absorption) Pernicious anemia Vegetarians / Vegans (low dietary B12) People taking metformin or acid reflux medications (PPIs) Post-bariatric or gastric-bypass patients Genetic variants in MTRR , MTR , or TCN2 What Has B12 Been Studied For
The American Association for the Study of Liver Diseases (AASLD) has provided recommendations for the identification of people who are at high risk of having MASLD and advanced fibrosis and these include obese, metabolic syndrome, and T2DM patients (69)
Most patients don't see significant weight loss in week one, though appetite suppression begins immediately
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