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Particularly under induced stress, PI3K/Akt exerts a cell-protective effect, enhancing expression of inflammatory cytokines and prosurvival signaling cascades (Hu et al., 2018

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In women, OS is implicated in various reproductive disorders, including polycystic ovary syndrome, endometriosis, and premature ovarian failure, leading to diminished oocyte quality, disrupted folliculogenesis, and poorer reproductive outcomes