Modulates growth-factor receptor expression on tendon fibroblasts, including growth-hormone receptor upregulation
Demonstrates collagen stimulation and skin improvement at 1-2mg daily doses n.d
Theoretical concerns regarding growth factor modulation and potential cancer interactions remain unsubstantiated by clinical evidence
A clinical series published in the Journal of Clinical Medicine found that patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) who received intermittent intravenous saline infusions over a 9-week period showed beneficial effects in managing symptoms of dysautonomia and postural orthostatic tachycardia syndrome (POTS)
Other reported mechanisms include activation of FAK-paxillin complexes (which help cells migrate and attach to surfaces during wound healing), JAK-2 signaling, and ERK1/2 pathway activity (Sikiric et al., Current Neuropharmacology, 2016
Your body already makes peptidestheyre short chains of amino acids that act as messengers, telling cells what to do