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Semaglutide, the GLP-1 medication sold as Wegovy and Ozempic, produces roughly 15% weight loss

It provides another data point for the value of glucagon receptor activation

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(PubMed) Thomas SR, Leichtweis SB, Pettersson K, et al

According to the American Diabetes Association (ADA), GLP-1 therapy is mainly used for managing type 2 diabetes by aiding in controlling blood sugar levels through stimulating insulin release and decreasing glucose production in the liver while also delaying the digestion process in the stomach