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The authors reported that intra-articular AOD-9604 injection in the rabbit osteoarthritis model produced macroscopic, histologic, and biomechanical evidence of cartilage preservation relative to untreated controls, with the combination of AOD-9604 plus hyaluronic acid yielding the most consistent chondroprotective effect [4]
Forgetting to remove air bubbles can lead to discomfort during injection
PMID 25824066
OPTIONS Study Phase 2b results announcement (AOD-9604 development terminated)
It hasnt happened since
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