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The deal with China-based manufacturer YaoPharma will focus on development, manufacture and commercialisation of its phase I GLP-1 drug YP05002

Simultaneously, GLP-1 stabilizes the endothelium by decreasing capillary permeability and activating eNOS, leading to increase NO production and improved microcirculation and tissue perfusion

reported greater weight loss in obese mice with the GLP-1/GIP/glucagon receptor triagonist compared to GLP-1 receptor agonists, GIP/GLP-1 receptor co-agonists and GLP-1/glucagon receptor agonists including semaglutide and tirzepatide [60]

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