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Duro-Castano A, Borrs C, Herranz-Prez V, Blanco-Ganda MC, Conejos-Snchez I, Armin A, et al
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10.24327/ijcar.2018.9866.1646 69 SinghS.VyasR.ChaturvediA.SisodiaR
Unlike many peptides that have only injectable research data, GHK-Cu has been tested in published human clinical trials specifically as a topical application with outcomes that compared favorably against gold-standard actives
the peptide is hydrophilic and relatively large, so most of a topical dose does not reach viable dermis without delivery enhancement