The peptide promoted tendon outgrowth from explants, enhanced tendon fibroblast migration in vitro, and increased cell survival under stress conditions
when there is no activity)
Higher efficacy Aside from pricing competition and label expansion, greater efficacy in HbA1c reduction and/or weight loss, reduced side-effects and increased patient convenience (eg an oral tablet rather than a subcutaneous injection) will also contribute to the success of new GLP-1s and associated weight loss medication
GLP-1 medications slow gastric emptying, which can increase bile acid exposure in the colon and potentially worsen existing diarrhea in some patients
Further, improving overall health and aiding with detoxification and liver function
An animal study reported that L-carnitine supplementation markedly reduced the concentrations of TNF-, IL-1b, and CRP in Wister rats