(PubMed) Bjelakovic G, Nikolova D, Gluud C
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When to Avoid PT-141 PT-141 should not be used in people with: Heart disease, such as a recent stroke, unstable angina, or severe heart failure Unmanaged high blood pressure Because PT-141 activates the bodys arousal pathways, it can place extra stress on the cardiovascular system, so medical guidance is essential
Therefore, the drug may overcome a challenge of diet and exercise, where the brain compensates for weight loss by lowering metabolic rate, making it difficult to maintain lower weight long-term
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