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Sections were stained with H&E or processed further as indicated

The peptides can complement surgical interventions, hormonal therapies, and lifestyle modifications rather than replacing them entirely

Sections were washed in PBS-0.05% Tween-20 and incubated with secondary antibodies (Alexa 594 anti-Rabbit and Alexa 488 anti-Chicken, Thermo Fisher Scientific) for 1 h in room temperature

Weight Regain: A Common Challenge Studies show that discontinuing GLP-1 agonists frequently leads to weight regain and a return of cardiometabolic issues that improved while on the medication.(3, 4) An analysis of 327 individuals who used GLP-1 medication for 68 weeks found that after stopping the treatment, they regained approximately two-thirds of the weight they had initially lost

Individuals with restrictive eating disorders, fasting behaviors, or weight-driven purging may be at increased risk of symptom reactivation and are not appropriate candidates

doi:10.1093/toxsci/kfm268 Hofmann AF