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Except for the beneficial effects in the model animals fed normal diets, LA treatment with the same dose significantly attenuated hepatic TG accumulation (via increasing ACC and decreasing FAS) in gene-mutant obesity animals fed an HFD (40% energy from fat) and high-cholesterol diet [88]

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Sections were blocked with 2.5% normal horse serum (Vector Laboratories) for 1 h, followed by 24 h of incubation with the following rabbit primary antibodies: anti-S100 (1:100, Abcam ab41548), anti-MAOB (1:100, Abcam ab175136, Santacruz sc-515354), and anti-ABAT (1:100, Abcam ab108249)

Uchikawa T, Yasutake A, Kumamoto Y, Maruyama I, Kumamoto S, Ando Y

Type I interferon in the pathogenesis of lupus

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