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GLP-1 receptor agonists stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning they only trigger insulin release when blood glucose levels are elevated

Patients who continued treatment with arGLP-1 sustained their excess weight loss over time, with positive outcomes observed even up to 34 years of continuous therapy

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Semaglutide works best when its monitored and adjusted over time

Liraglutide and semaglutide are both drugs for T2D, which are now being used/researched for obesity (semaglutide is not yet approved)