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Vitamin B12 supplements are generally considered safe

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Longer-acting GLP-1 analogs that can be administered once each month are currently in clinical trials

Dysesthesia The TRIUMPH-4 trial data revealed a notable safety signal: dysesthesia (abnormal sensations like tingling, burning, or numbness) was reported in 8.8% of participants on the 9 mg dose and 20.9% on the 12 mg dose of retatrutide