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In that study, arginine depletion inhibited Warburg effect, reduced aerobic glycolysis, increased glutamine anaplerosis, oxidative phosphorylation, and serine biosynthesis together in different cancer cell types in vitro [147]

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In accordance with previous reports 36,37 , our GSEA analysis revealed positive enrichment for genes of the mTORC1 signaling pathway in Gclc -sufficient MZB compared to FoB (Fig

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