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The corresponding placebo-group changes were small. The pooled Phase 3 analysis included more than 800 participants and confirmed a significant treatment effect on visceral adipose tissue. These results formed the basis of tesamorelins FDA-approved prescription indication

Because of this, retatrutide is thought to be more effective than Wegovy, which only binds to GLP-1 receptors, and Mounjaro, which is a dual agonist that mimics the effects of GLP-1 and GIP

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Common side effects are nausea, vomiting, diarrhea, and constipation

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