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However, due to the large molecular size, topical glutathione may have limited skin penetration, though it can still support skin health when combined with other active ingredients like vitamin C, kojic acid, or niacinamide

Biochimica et Biophysica Acta - General Subjects , 1830(5), 31433153

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Mortality was assessed based on lack of movement in response to stimulation and discolouration (melanisation) of the cuticle

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Levels decrease with age, leading to thinner skin, loss of elasticity, slower healing, and more visible lines