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FDA banned it in late 2023 "Category 2: Substance with Safety Concerns" Why the FDA banned it: Potential immune reactions (immunogenicity) Manufacturing impurities in compounded versions Complete lack of human safety data Risk of contamination Legal status: NOT FDA-approved Illegal to compound in pharmacies Banned by WADA for athletes Possession not illegal (it's not a DEA scheduled substance) Sold online as "research chemical" 2

Each pathway responds differently to temperature changes, creating complex stability profiles that vary between peptide compounds

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Joint pain may involve cartilage, ligaments, tendons, nerves, autoimmune conditions, or referred pain