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In a phase II study of the long-acting GLP-1RA efpeglenatide (4 mg once weekly, 6 mg once weekly, 6 mg once every 2 weeks, and 8 mg once every 2 weeks), patients with obesity and without diabetes had statistically significant reductions in body weight compared with placebo after 20 weeks of treatment (differences in least squares means were 6.3 to 7.2 kg
Clinical and lab studies find small improvements in sperm quality and oocyte resilience when certain peptides are combined with lifestyle or medical interventions
Statistical parameters reveal a low predictive power, suggesting that the type of treatment does not substantially impact on the metabolic profile
Caravati EM, Erdman AR, Christianson G, et al
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