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Most peptides are broken down in the digestive system before they enter the bloodstream, which makes them ineffective when taken orally
Mostofsky, View ORCID ProfileRichard A.E
This is characterized by an elimination phase, lasting 6 weeks to 6 months, in which grains, legumes, nuts seeds, dairy, eggs, coffee and alcohol are forbidden
Significant weight changes usually become noticeable within the first month or two
For most individuals, oral dosage forms offer a more convenient formulation compared to injections, especially for those who may not be comfortable with needles
The safety profile was broadly consistent with earlier retatrutide studies and the wider incretin drug class, with diarrhoea, nausea and constipation among the most common adverse events
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