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However, it is not clear how GLP-1 RA regulates ER stress

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Intestinal epithelial cells take up metformin through transporters located on the inner surface of the intestinal epithelium such as plasma monoamine transporter protein (PMAT) and organic cation transporter protein 3 (OCT3) (Figure 1)

Hypersensitivity reactions Severe allergic reactions are documented, presenting variously with rash, urticaria, angioedema, and anaphylaxis

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