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In reality, up to 70% of patients stop GLP-1 treatment within a year most often due to: High cost (GLP-1s can cost $1,000+ per month without insurance) Loss of insurance coverage for weight loss treatment Side effects such as nausea, diarrhea, constipation, or fatigue A Misconceptions some patients stop once they lose initial weight, believing they no longer need the medication 2

To prepare the injection, combine the contents of the ampoule with the vial, followed by the addition of 5 ml of sterile water

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A long-acting release form of exenatide (exenatide ER, Bydureon) was approved by the FDA in 2012, becoming the first once-weekly injection of a GLP-1RA for adults with T2DM [ Table 2 ]

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FDA has issued warnings about injectable glutathione after contamination events