Thiamin supplements may also help for people who experience: malabsorption syndrome severe, prolonged vomiting gastric bypass surgery renal replacement therapy hyperthyroidism People who are pregnant, lactating, or use diuretics may also benefit from vitamin B1 supplements
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However, more human studies are needed to confirm these findings (7)
In diazepam chronically treated mice, it attenuated diazepam tolerance (provoked by later acute administration of diazepam together with convulsant) and postponed physical dependence/withdrawal effects (provoked by later administration of isoniazid)