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Precaution is recommended due to the metabolic pathways involved in early growth
In general, the level of guidance and support that patients receive in clinical trials doesnt accurately reflect the experience they would have at a quality real-world weight-loss service
The official guidance is that it should not be allowed below 36 degrees or above 86 degrees Fahrenheit
Duration: 1 to 5 days for most people, resolving as the body adapts
Diabetes Metab Res Rev 36(5):e3292
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