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SAM donates methyl groups for many cellular reactions
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Because its derived from a gastric protein, its uniquely stable in the harsh environment of the stomach
But the research has been very clear that taking glutathione orally has been unsuccessful and possibly even dangerous because you are putting a protein in the body that if not accepted could be looked at as an invader
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Many people struggle here due to low stomach acid, gastrointestinal conditions, certain medications, or age-related changes
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