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GLP-1 receptor agonists work by mimicking the action of naturally occurring GLP-1, a hormone that stimulates insulin secretion in response to food intake, suppresses glucagon release, slows gastric emptying, and promotes satiety

To shed light on the interactions of the enzyme with the natural substrates, we docked flavan-3,3,4-triol ( 4 ) and flavan-3-on-4-ol ( 7 ) into the active pocket of the crystal structure of Pt GSTF8 obtained with ()-catechin ( 12 ) (Extended Data Fig

J., Bleich, S

Garca Garca, E., & Jimnez Varo, I

GLP-1 Agonists as a Complementary Tool: In contrast, while GLP-1 agonists can aid in reducing body weight and improving health markers, they are less likely to produce the transformative weight loss that is often necessary for significant disease resolution in morbidly obese patients

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