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GLP-1 Peptide Therapeutics: From Metabolic Breakthrough to Multi-Disease Potential 14 May 2026 How GLP-1 Therapies Are Evolving into a Multi-Indication Platform Glucagon-like peptide-1 (GLP-1) is a naturally occurring peptide hormone released in the gut after eating, where it plays a central role in regulating blood glucose levels and appetite

For tirzepatide versus dulaglutide, MACE risk was 1.4% versus 1.8% (HR 0.87

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Through lipidation, a process where a fatty acid chain is attached to the peptide molecule, researchers gave cagrilintide a half-life long enough for once-weekly dosing

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