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One had diabetic papillitis (optic nerve swelling), did not lose vision and continued on the drug

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Oral Melanotic Macule An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth

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Avoid carbonated drinks and straws, which introduce air into an already sluggish system

In the SURPASS and SURMOUNT trials, nausea was reported in up to 32% of participants, diarrhea in 23%, vomiting in 12%, and constipation in 11%