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Seek prompt medical advice if you experience: Severe or rapidly worsening joint pain that significantly impairs function or mobility A hot, swollen, very painful joint with fever this could indicate septic arthritis requiring SAME-DAY emergency hospital assessment Symptoms of severe allergic reaction after B12 injection (breathing difficulty, facial/tongue swelling, widespread hives, dizziness/collapse) call 999 immediately Systemic symptoms such as unexplained weight loss, night sweats, or profound fatigue Neurological symptoms including weakness, numbness, balance problems, or cognitive changes Symptoms affecting multiple joints simultaneously, particularly if symmetrical (both hands, both knees) Morning stiffness lasting more than 30 minutes , which may suggest inflammatory arthritis Your GP will conduct a thorough clinical assessment, including detailed history-taking and physical examination
Bee venom: from venom to drug
For oral GHK-Cu, the bioavailability is generally lower than with injections or IV administration because digestive enzymes and stomach acid break down peptides
While a high dietary intake of the vitamin rarely causes high vitamin B12, excess usually results from supplementation or injections