The medication is also approved for the treatment of moderate to severe obstructive sleep apnea (OSA)
Most clinical evidence comes from dermatology and wound-healing studies with sample sizes under 100 participants
Clinical implications of estimated glomerular filtration rate dip following sodium-glucose cotransporter-2 inhibitor initiation on cardiovascular and kidney outcomes
10.1007/s12272-025-01574 84 LuX.XuC.DongJ.ZuoS.ZhangH.JiangC.et al (2021)
It is essential to consider this information when making treatment decisions ( versus the placebo group (Peto OR [95% CI] 1.05 [0.781.40], p = 0.76 and 1.12 [0.771.63], p = 0.56, respectively) ( Furthermore, another meta-analysis provided evidence that contradicts the notion of an increased risk of acute pancreatitis in individuals treated with GLP-1 agonists ( n = 33,350), and it was determined that GLP-1 agonists do not pose an increased risk of pancreatitis compared to controls
Many of the benefits are lost when food is cooked, however