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This study of semaglutide demonstrates the effectiveness of a new pathway to reduce the excess risk associated with obesity of important and potentially deadly cardiovascular complications. One limitation of the trial is that only patients with pre-existing cardiovascular disease were included
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regain often occurs on discontinuation (~0.8 kg/month for GLP-1s)
Even in binge eating disorder, appetite reduction may not address the emotional roots of the condition
The pills are easier to store
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