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This limitation is expected to be addressed by a dedicated two-phased validation strategy in future work: Phase I Retrospective RNA Validation: This involves prioritizing an intensive search for and inclusion of any suitable independent external RNA-seq cohorts with adequate clinical follow-up data

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Factors That May Affect Appropriateness According to general clinical guidance referenced in published sources, growth hormone secretagogues may not be appropriate for individuals with certain contraindications including active malignancies, uncontrolled diabetes, or other conditions that a clinician would evaluate during the prescribing process

2020;45(Suppl 1):4360

doi: 10.1016/j.bbadis.2013.01.008 50 DumanR