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If you've been taking oral B12 supplements without feeling a difference, a shot is the most reliable way to find out whether the issue is your B12 levels or something else

These symptoms usually improve after a few weeks as your body adjusts

Regardless, the FDA has reported that there has been no connection found between GLP-1s and suicidal thoughts or behaviorsbut they are still researching the topic

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It works by depleting substance P, a neurotransmitter involved in pain signaling

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