Oral mucosal melanin hyperpigmentation is common and may be physiological or pathological, and in either case the pattern of distribution and the intensity of the melanosis are variable
For instance, New Zealand guidelines recommend offering GLP1RAs to all patients with HbA1c levels above target, especially when GLP1RA use would provide additional reductions in cardiovascular risk and/or permit reduction or cessation of other therapies that contribute to weight gain or hypoglycemia
Greene ponders, is there a potential risk for something similar to what you see with synthetic growth hormone
Investors should watch its Phase 3 readouts, regulatory filing timeline, adverse event profile, discontinuation rates, and performance in patients with comorbidities such as sleep apnea, diabetes, osteoarthritis, cardiovascular risk, and liver disease
(9) S Bhalla, S Mehan, A Khan, and M U Rehman (2022) Protective role of IGF-1 and GLP-1 signaling activation in neurological dysfunctions Neuroscience and Biobehavioral Reviews, 2022 Nov, Volume 142, Page 104896
Yes, it is common for tirzepatide to cause a late period, primarily due to the stress of rapid weight loss on the body