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De-dimerization of PTB is catalyzed by PDI and is involved in the regulation of p53 translation

The Biological Connection to Hair Pigment Hair color is determined by a pigment called melanin, which is produced by specialized cells known as melanocytes

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Reconstituted LIPO-C remains stable for a maximum of 72 hours when stored at 28C in a refrigerator

Without sufficient NAD+, these enzymes cannot functionwhich explains why the decline in NAD+ with age leads to a cascade of cellular dysfunctions (Katsyuba et al., Nat Metab 2020)

Explore NLRP3 inflammasome genetics: How variants drive chronic inflammation in Alzheimers, diabetes, and autoimmune diseases