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Until such data are available, prescribing decisions should be individualised and based on careful assessment of risks and benefits

ANOVAs or two-tailed t -tests were performed throughout, with data visually confirmed as approximately normally distributed

Many patients qualify with a BMI of 27 or higher if they also have one or more weight-related medical conditions

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Zhang Z, Xu X, Zhang D, Zhao S, Wang C, Zhang G, et al

This suggests that when we look at body composition ratios and functional outcomes rather than just absolute numbers, the picture is more encouraging than the early STEP 1 data implied