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This approach isolates the effect of increasing or decreasing training load relative to one's usual routine , rather than absolute exercise volume

Prez-Aizpurua X, Garranzo-Ibarrola M, Simn-Rodrguez C, Garca-Cardoso JV, Chvez-Roa C, Lpez-Martn L, et al

This process is exacerbated by smoking, pollution, exposure to UV or ionizing radiation, eating fried foods or those cooked at high temperatures, as well as engaging in high-intensity exercise (12)

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Although HIF-2 has biochemical characteristics similar to those of HIF-1, the metabolic role of HIF-2 in a low-oxygen environment is relatively unknown 68