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The molecule is too big to pass through your skin barrier so intact Collagen physically can't get past the surface

Some individuals have an immune response to these proteins, leading to inflammation and gut dysbiosis

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The frequency of treatments varies based on individual goals and health conditions

It enrolled adults with a body mass index of 30 or greater, or 27 or greater with at least one weight-related comorbidity, and randomized them across multiple retatrutide dose arms (1 mg, 4 mg, 8 mg, and 12 mg weekly) versus placebo